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pentobarbital decreases results of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Coadministration of CYP3A4 inducers could lower sufentanil concentrations and efficacy, perhaps precipitating withdrawal syndrome in people which have made Actual physical dependence to sufentanil. Discon
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